The gammaCore SapphireTM is the first and only FDA cleared non-invasive device for treating and preventing headache pain via the vagus nerve. It is small, handheld, and portable for convenient use anywhere. For acute use, it provides fast-acting, long-lasting pain relief with just a few 2-minute treatments. For prevention, treating twice daily can lead to more headache-free days. The device activates the vagus nerve with gentle electrical stimulation through the skin, blocking pain signals to alleviate and prevent headaches.